HbA1c as a time predictive biomarker for an additional islet autoantibody and type 1 diabetes in seroconverted TEDDY children.
Falastin SalamiRoy TamuraLu YouLernmark ÅkeHelena Elding LarssonMarkus LundgrenJeffrey KrischerAnette-Gabriele ZieglerJorma ToppariRiitta VeijolaMarian RewersMichael J HallerWilliam HagopianBeena AkolkarCarina Törnnull nullPublished in: Pediatric diabetes (2022)
In conclusion, increased HbA1c is a reliable time predictive marker for type 1 diabetes onset. The increased rate of increase of HbA1c from first to third autoantibody and the decrease in HbA1c predicting the development of IA-2A are novel findings proving the link between HbA1c and the appearance of autoantibodies.