Sequential disruption of ALV host receptor genes reveals no sharing of receptors between ALV subgroups A, B, and J.

Hong Jo LeeKyung Je ParkKyung Youn LeeYongxiu YaoVenugopal NairJae-Yong Han

Published in: Journal of animal science and biotechnology (2019)

Simultaneous editing of multiple receptors to block infection by different subgroups of ALV confirmed that ALV subgroups A, B, and J do not share host receptors. This strategy could be used to generate cells resistant to multiple viral pathogens that use distinct receptors for cell entry.

Keyphrases

induced apoptosis
crispr cas
single cell
oxidative stress
cell cycle arrest
health information
cell death
cell proliferation
endoplasmic reticulum stress
multidrug resistant
antimicrobial resistance
bioinformatics analysis
genome wide analysis