Minimal prevalence of HPV vaccination and common occurrence of high-risk HPV types in pregnant women with HIV: data from a national study in Italy.
Marco FloridiaGiulia MasuelliBeatrice TassisValeria M SavasiMatilde SansoneArsenio SpinilloLaura FranceschettiGiovanni GuaraldiCarmela PinnettiSerena DalzeroAlessandra MeloniAntonella VimercatiGiuliana SimonazziEnrica TamburriniMarina Ravizzanull nullPublished in: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology (2022)
Among 733 pregnant women with HIV followed between 2013 and 2021, only 8 (1.1%) had prior HPV vaccination. One had low-grade squamous intraepithelial lesions [LSIL], and none had HPV type information. Among the 725 non-vaccinated women, 578 (79.7%) had information on cervical cytology. Rate of cytologic abnormalities in this group was 20.6% (0.2% atypical glandular cells of undetermined significance [AGC], 1.7% atypical squamous cells of undetermined significance [ASC-US], 11.1% LSIL, and 7.6% high-grade squamous intraepithelial lesions [HSIL]). Among 56 women with HPV type information, 75.0% carried high risk types, with similar occurrence in women with and without cytologic abnormalities, 30.4% had multiple high-risk types, and 75.9% carried at least one of the types included in the currently recommended 9-valent vaccine.
Keyphrases
- high grade
- low grade
- induced apoptosis
- pregnant women
- antiretroviral therapy
- hiv positive
- hiv infected
- human immunodeficiency virus
- cell cycle arrest
- hepatitis c virus
- hiv testing
- hiv aids
- health information
- risk factors
- men who have sex with men
- endoplasmic reticulum stress
- quality improvement
- social media
- south africa
- insulin resistance
- signaling pathway
- big data
- deep learning
- pregnancy outcomes