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Formulation Consideration of Medicated Chewing Gum: A Review.

Kishan BobeYoesh SuryawanshiVirendra GomaseMuizz KachhiChandrashekhar Bobade
Published in: Recent advances in drug delivery and formulation (2024)
In recent times, technological and scientific advances have been made in studying and developing orally delivered medication. Such studies demonstrate the importance of the oral route among patients. The accuracy of drug delivery is very important to achieve a successful therapeutic effect in the case of various pharmaceutical products. A novel drug delivery system adds new benefits or advantages to a drug. This review covers all the aspects of medicated chewing gum (MCG) as a new drug delivery method, including the benefits and drawbacks, manufacturing methods, type of MCG, composition of chewing gum, evaluation parameters, factors that affected the release of API, its pharmaceutical significance, various marketed chewing gum and chewing gum packaging. Chewing gum as a drug delivery system has the potential to cure or prevent various indications, such as analgesic, CNS stimulation, smoking cessation, motion sickness, and treatment and prevention of dental caries or gingivitis. Pharmaceutical distribution to the oral mucosa can be made more convenient and enticing with the help of MCG. Compared to conventional techniques, this delivery system has a longer-lasting effect, which makes it a viable option for treating digestive problems, headaches, migraines, coughing, anxiety, and allergies.
Keyphrases
  • drug delivery
  • smoking cessation
  • replacement therapy
  • cancer therapy
  • healthcare
  • mental health
  • emergency department
  • drug release
  • spinal cord
  • blood brain barrier
  • risk assessment
  • electronic health record
  • human health