MALDI imaging in Fabry nephropathy: a multicenter study.

Vincenzo L'ImperioAndrew SmithAntonio PisaniMaria D'ArmientoViviana ScolloStefano CasanoRenato Alberto SinicoManuela NebuloniAntonella TosoniFederico PieruzziFulvio MagniFabio Pagni

Published in: Journal of nephrology (2019)

The present study demonstrated the feasible application of MALDI-MSI in the analysis of FN FFPE renal biopsies, allowing the detection of putative signatures for phenotypic distinction and demonstrating genetic classification capabilities.

Keyphrases

mass spectrometry
genome wide
high resolution
machine learning
deep learning
replacement therapy
loop mediated isothermal amplification
gene expression
heart failure
label free
hypertrophic cardiomyopathy
copy number
atrial fibrillation
real time pcr
smoking cessation