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Modelling the benefits of long-acting or transmission-blocking drugs for reducing Plasmodium falciparum transmission by case management or by mass treatment.

Michael T BretscherJamie T GriffinAzra C GhaniLucy C Okell
Published in: Malaria journal (2017)
These results emphasise the importance of increasing access to treatment for routine case management, and the potential value of choosing first-line anti-malarial treatment policies according to local malaria epidemiology to maximise impact on transmission. There is no indication that the optimal drug choice should differ between delivery via case management or MDA.
Keyphrases
  • plasmodium falciparum
  • public health
  • emergency department
  • cell proliferation
  • climate change
  • combination therapy
  • cell death
  • cell cycle arrest