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Synthetic Cooling Agent and Candy Flavors in California-marketed "non-Menthol" Cigarettes.

Sairam V JabbaHanno C ErythropelPaul T AnastasJulie B ZimmermanSven-Eric Jordt
Published in: bioRxiv : the preprint server for biology (2023)
Tobacco companies have replaced menthol with the synthetic cooling agent, WS-3, in California-marketed "non-menthol" cigarettes. WS-3 creates a cooling sensation similar to menthol, but lacks menthol's characteristic "minty" odor. The measured WS-3 content is sufficient to elicit cooling sensations in smokers, similar to menthol, that facilitate smoking initiation and act as a reinforcing cue. Regulators need to act quickly to prevent the tobacco industry from bypassing menthol bans by substituting menthol with synthetic cooling agents, and thereby thwarting smoking cessation efforts.
Keyphrases
  • smoking cessation
  • replacement therapy
  • transcription factor