IFN-γ, SCF, MIP1b and IL-16 Were Associated with Risk of Diabetic Nephropathy: A Mendelian Randomization Study.

Li AnXiaomei RenYe PanWei GaoLiqun RenJing WangYao Wang

Published in: Diabetes, metabolic syndrome and obesity : targets and therapy (2024)

Our MR results based on genetic data contribute to a better understanding of the pathogenesis of DN and provide evidence for a causal effect of inflammatory factors on DN. These findings support targeting specific inflammatory factors to alleviate DN risk.

Keyphrases

diabetic nephropathy
oxidative stress
immune response
magnetic resonance
dendritic cells
electronic health record
cancer therapy
magnetic resonance imaging
contrast enhanced
gene expression
machine learning
data analysis