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GSDMD induces hepatocyte pyroptosis to trigger alcoholic hepatitis through modulating mitochondrial dysfunction.

Yandi XieZilong WangGuangjun SongHui MaBo Feng
Published in: Cell division (2024)
GSDMD induces hepatocyte pyroptosis by modulating mitochondrial dysfunction during AH-induced inflammation and liver injury. These findings may pave the way to develop new therapeutic treatments for AH.
Keyphrases
  • liver injury
  • drug induced
  • nlrp inflammasome
  • signaling pathway
  • oxidative stress
  • diabetic rats
  • high glucose
  • stress induced