Evaluation of Delirium in Critically Ill Patients Prescribed Melatonin or Ramelteon.
Natasha RomeroKevin M DubeKenneth E LupiJeremy R DeGradoPublished in: The Annals of pharmacotherapy (2021)
Therapy with melatonin, ramelteon, and no melatonin receptor agonist resulted in similar rates of delirium in a mixed ICU population. Despite significant differences in agitation, sedation, and medication utilization, there was no differences in the clinical outcomes evaluated.