TorsinA regulates the LINC to moving nuclei.

Published in: The Journal of cell biology (2017)

How LINC complexes are regulated to connect nuclei to the cytoskeleton during nuclear migration is unknown. Saunders et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201507113) show that the AAA+ ATPase torsinA and its partner LAP1 are required for nuclear migration during fibroblast polarization by mediating the dynamics of LINC complexes.

Keyphrases

long non coding rna
long noncoding rna
cell proliferation
single cell
hepatitis c virus
endoplasmic reticulum