The Immunogenomic Landscape of Neuroendocrine Prostate Cancer.
Bhavneet BhinderAlison FergusonMichael SigourosManik UppalAhmed G ElsaeedRohan BarejaHussein AlnajarKenneth Wha EngVincenza ConteducaAndrea SbonerJuan-Miguel MosqueraOlivier ElementoHimisha BeltranPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
NEPC is characterized by a relatively immune-depleted tumor immune microenvironment compared with other primary and metastatic prostate adenocarcinoma except in a minority of cases. These findings may inform development of immunotherapy strategies for patients with advanced prostate cancer.