Adalimumab mitigates ovarian ischemia-reperfusion injury in rats by regulating oxidative stress, apoptosis and resolution of inflammation.
Fatma BeyazitBaşak BüyükHakan TurkonSait ElmasMetehan UzunPublished in: The journal of obstetrics and gynaecology research (2018)
Adalimumab therapy in rats attenuated I/R induced ovarian injury, possibly suppressing inflammation, inhibiting oxidative stress, and altering apoptotic pathways.
Keyphrases
- oxidative stress
- diabetic rats
- rheumatoid arthritis
- ischemia reperfusion injury
- dna damage
- induced apoptosis
- signaling pathway
- juvenile idiopathic arthritis
- cell death
- high glucose
- ulcerative colitis
- single molecule
- systemic lupus erythematosus
- drug induced
- stem cells
- anti inflammatory
- bone marrow
- mesenchymal stem cells
- radiation induced