Cellular dosimetry of [177Lu]Lu-DOTA-[Tyr3]octreotate radionuclide therapy: the impact of modeling assumptions on the correlation with in vitro cytotoxicity.

Giulia TamborinoMarijke De Saint-HubertLara StruelensDayana C SeoaneEline A M RuigrokAn AertsWiggert A van CappellenMarion de JongMark W KonijnenbergJulie Nonnekens

Published in: EJNMMI physics (2020)

Our results demonstrate that modeling of cellular and organelle geometry is crucial to perform accurate in vitro dosimetry.

Keyphrases

monte carlo
pet ct
high resolution
pet imaging
bone marrow