Variant analyses of candidate genes in orofacial clefts in multi-ethnic populations.

Mary LiJoy OlotuCarmen J Buxo-MartinezPeter A MosseyDeepti AnandTamara BuschAzeez AladeLord Jephthah Joojo GowansMekonen EsheteWasiu Lanre AdeyemoThirona NaickerWaheed O AwotoyeSagar GuptaChinyere AdelekeValeria BravoSiyong HuangOlatunbosun O AdamsonAda M TorañoCarolina A BelloMairim SotoMarilyn SotoRicardo LedesmaMyrellis MarquezJose F CorderoLydia M Lopez-Del ValleMaria I SalcedoNatalio DebsAline PetrinHannah MalloyKhalid ElhadiOlutayo JamesMobolanle O OgunleweFekir AbateAbiye HailuIbrahim MohammedPaul GravemMilliard DeribewMulualem GessesMohaned HassanJohn PapeSolomon Obiri-YeboahFareed K N ArthurAlexander A OtiPeter DonkorMary L MarazitaSalil A LachkeAdebowale A AdeyemoJeffrey C MurrayAzeez Butali

Published in: Oral diseases (2021)

This study provides evidence that variants in SHH, RORA, MRPL53, ACVR1, and GDF11 may contribute to risk of orofacial clefts in various populations.

Keyphrases

copy number
genetic diversity
gene expression
dna methylation