Body composition, adipokines, FGF23-Klotho and bone in kidney transplantation: Is there a link?
Stefana Catalina BilhaStefana Catalina BilhaDaniela ConstantinescuMariana Pavel-TanasaPetru CiangaAdrian C CovicDumitru D BranisteanuPublished in: Journal of nephrology (2021)
Age, PTH, time on dialysis and lean mass are among the main bone density predictors in long-standing KT patients. The bone impact of adipokine dysregulation and of α-Klotho merits further investigations in KT-MBD. Preserving lean mass for improved bone outcomes should be part of KT-MBD management on the long-term.
Keyphrases
- bone mineral density
- body composition
- postmenopausal women
- end stage renal disease
- kidney transplantation
- chronic kidney disease
- soft tissue
- resistance training
- bone loss
- ejection fraction
- bone regeneration
- adipose tissue
- type diabetes
- skeletal muscle
- metabolic syndrome
- weight loss
- glycemic control
- patient reported
- high intensity