Patterns of nodal spread in stage III NSCLC: importance of EBUS-TBNA and 18F-FDG PET/CT for radiotherapy target volume definition.
Maja GuberinaKaid DarwicheHubertus HautzelChristoph PöttgenNika GuberinaThomas GaulerTill PloenesLale UmutluDirk TheegartenClemens AignerWilfried E E EberhardtMartin MetzenmacherMarcel WieswegRüdiger Karpf-WisselMartin SchulerKen HerrmannMartin StuschkePublished in: Radiation oncology (London, England) (2021)
Frequent patterns of LN-metastatic spread could be defined by EBUS-TBNA and PET and discrepancies in the pattern were seen between both methods. EBUS-TBNA showed more lobe and tumor laterality specific patterns of LN-metastases than PET and skipped lymph node stations were rare. These systematic relations offer the opportunity to further refine multi-parameter risk of LN-involvement models for target volume delineation based on pattern of spread by EBUS-TBNA and PET.