Pediatric RSV Diagnostic Testing Performance: A Systematic Review and Meta-analysis.
Chukwuemeka OnwuchekwaJessica AtwellLaura Mora MoreoSonia MenonBelen MachadoMariana SiapkaNeha AgarwalMichelle RubbrechtZuleika Aponte-TorresMark RozenbaumDaniel CurcioHarish NairWarren V KalinaHilde VrolingBradford GessnerElizabeth BegierPublished in: The Journal of infectious diseases (2023)
RT-PCR was the most sensitive pediatric RSV diagnostic test. Adding multiple specimens did not substantially increase RSV detection, but even small proportional increases could result in meaningful changes in burden estimates. The synergistic effect of adding multiple specimens should be evaluated.