Distribution of Aspergillus Species and Prevalence of Azole Resistance in Respiratory Samples From Swiss Tertiary Care Hospitals.
Silvio RagozzinoDaniel GoldenbergerPatrick R WrightStefan ZimmerliKonrad MühlethalerDionysios NeofytosArnaud RiatKatia BoggianOliver NolteAnna ConenHans FankhauserPeter W SchreiberReinhard ZbindenFrederic LamothNina KhannaPublished in: Open forum infectious diseases (2021)
Among 400 Aspergillus species from respiratory samples in Switzerland, Aspergillus fumigatus was the most frequent species. Non- fumigatus Aspergillus spp were more prevalent among solid organ transplant recipients and after azole exposure. Azole resistance was detected in 4 A fumigatus isolates, 3 of them with the "environmental" mutation TR 34 /L98H in the cyp51A gene.