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Distribution of Aspergillus Species and Prevalence of Azole Resistance in Respiratory Samples From Swiss Tertiary Care Hospitals.

Silvio RagozzinoDaniel GoldenbergerPatrick R WrightStefan ZimmerliKonrad MühlethalerDionysios NeofytosArnaud RiatKatia BoggianOliver NolteAnna ConenHans FankhauserPeter W SchreiberReinhard ZbindenFrederic LamothNina Khanna
Published in: Open forum infectious diseases (2021)
Among 400 Aspergillus species from respiratory samples in Switzerland, Aspergillus fumigatus was the most frequent species. Non- fumigatus Aspergillus spp were more prevalent among solid organ transplant recipients and after azole exposure. Azole resistance was detected in 4 A fumigatus isolates, 3 of them with the "environmental" mutation TR 34 /L98H in the cyp51A gene.
Keyphrases
  • candida albicans
  • tertiary care
  • cell wall
  • genetic diversity
  • healthcare
  • risk factors
  • respiratory tract
  • copy number
  • gene expression
  • dna methylation
  • risk assessment
  • genome wide identification
  • life cycle