Predictors of local recurrence and its impact on survival after glansectomy for penile cancer: time to challenge the dogma?
Eduard RousselEline PeetersJoren VanthoorGiorgio BozziniAsif MuneerBen AyresDenosshan SriNick WatkinRohit BhattarArie ParnhamVijay SangarMaurice LauGregory A JoiceTrinity J BivalacquaJuan J ChipolliniPhilippe E SpiessGeorgios HatzichristodoulouLieke de VriesOscar R BrouwerMaarten Albersennull nullPublished in: BJU international (2020)
Pathological T3 stage and presence of high-grade disease were independent histopathological predictors of LR after glansectomy for primary pSCC, which allowed risk stratification into three groups with significantly different risk of developing LR. Additionally, LR is related to poor OS and CSS, indicating that LR is a manifestation of underlying aggressive disease and clearly challenging the dogma of using organ-sparing surgery whenever possible since survival is unaffected by higher LR rates.