Diurnal rhythm of urinary aquaporin-2 in children with primary monosymptomatic nocturnal enuresis.
Nehal AbdelhamidMohamed A Abd AlmawlaAliaa A. WahbyMervat IsmailHani Abdelsalam ElmikatyHanan M HamedIngy AshmawyBatoul Mohamed Abdel RaoufEnas Mokhtar AbdelhamidHassan M SalamPublished in: Turkish journal of medical sciences (2023)
Primary monosymptomatic nocturnal enuresis in children could be associated with reduction of urine excretion of AQP-2 at night. Urine AQP-2 is significantly correlated with urine osmolality. Therefore, it may be a noninvasive biomarker of hydration status in children with PMNE, with good sensitivity and specificity.