Docking Study, Synthesis, and Anti-Inflammatory Potential of Some New Pyridopyrimidine-Derived Compounds.

Mohamed Abdelwahab AbdelgawadMohammad M Al-SaneaArafa MusaMohammed ElmowafyAshraf K El-DamasyAmany A AzouzMohammed M GhoneimRania B Bakr

Published in: Journal of inflammation research (2022)

in the active site of COX-2 enzyme showed that these compounds implied interaction and binding motif similar to the cocrystallized ligand bromocelecoxib.

Keyphrases

anti inflammatory
molecular dynamics simulations
protein protein
human health
risk assessment
small molecule
dna binding
transcription factor