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Interaction of mammographic breast density with menopausal status and postmenopausal hormone use in relation to the risk of aggressive breast cancer subtypes.

Lusine YaghjyanRulla M TamimiKimberly A BertrandChristopher G ScottMatthew R JensenV Shane PankratzKathy BrandtDaniel VisscherAaron NormanFergus CouchJohn ShepherdBo FanYunn-Yi ChenLin MaAndrew H BeckSteven R CummingsKarla KerlikowskeCeline M Vachon
Published in: Breast cancer research and treatment (2017)
Our findings suggest that associations of mammographic density with breast cancer risk differ by tumor aggressiveness. While there was no strong evidence that these associations differed by menopausal status or hormone therapy, they did appear more prominent among current estrogen+progesterone users.
Keyphrases
  • breast cancer risk
  • estrogen receptor
  • stem cells
  • mesenchymal stem cells
  • postmenopausal women
  • bone mineral density