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The histamine system and cognitive function: An in vivo H3 receptor PET imaging study in healthy volunteers and patients with schizophrenia.

Atheeshaan ArumuhamMatthew M NourMattia VeroneseEllis Chika OnwordiEugenii A RabinerOliver D Howes
Published in: Journal of psychopharmacology (Oxford, England) (2023)
These findings indicate H3R in the DLPFC might play a role in executive function and this is disrupted in schizophrenia in the absence of major alterations in H3R availability as assessed using a selective radiotracer for H3R. This provides further evidence for the role of H3R in CIAS.
Keyphrases
  • pet imaging
  • bipolar disorder
  • positron emission tomography