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Endometrial scratching in unexplained repeated implantation failure causes two competing forces, angiogenesis and anti-angiogenesis: An RCT study.

Samaneh AghajanpourFereshteh MehraeinFatemehsadat AmjadiZahra ZandiehFirouzeh GhaffariKhashayar AflatoonianElham HosseiniMehrdad BakhtiyariReza Aflatoonian
Published in: International journal of reproductive biomedicine (2024)
ES induced significant alterations in the expression of angiogenesis-related genes, with notable up/downregulation of key angiogenic/antiangiogenic factors. These findings enhance our understanding of the molecular responses triggered by ES, underscoring the potential influence of ES on the complex processes of angiogenesis crucial for implantation.
Keyphrases
  • endothelial cells
  • vascular endothelial growth factor
  • high glucose
  • wound healing
  • signaling pathway
  • diabetic rats
  • oxidative stress
  • climate change
  • drug induced
  • human health
  • stress induced