Is sibship composition a risk factor for childhood asthma? Systematic review and meta-analysis.
Daniil LisikSaliha Selin Özuygur ErmisAthina IoannidouGregorio Paolo MilaniSungkutu NyassiGiulia Carla Immacolata SpolidoroHannu KankaanrantaEmma GoksörGöran WennergrenBright Ibeabughichi NwaruPublished in: World journal of pediatrics : WJP (2023)
Being second-born or later and having at least one sibling is associated with a slightly increased risk of temporary wheezing in infancy. In contrast, being second-born or later is associated with marginal protection against asthma. These associations appear to have weakened since the turn of the millennium, possibly due to lifestyle changes and socioeconomic development. Video Abstract.
Keyphrases
- chronic obstructive pulmonary disease
- lung function
- gestational age
- low birth weight
- allergic rhinitis
- magnetic resonance
- cardiovascular disease
- physical activity
- weight gain
- preterm infants
- sensitive detection
- cystic fibrosis
- early life
- weight loss
- type diabetes
- preterm birth
- living cells
- air pollution
- magnetic resonance imaging
- childhood cancer
- computed tomography