Identification of Novel MicroRNAs Targeting SARS-CoV-2 through the Regulation of TMPRSS2/PI3K/AKT/PTEN Alignment in Lung Cancer: An in Silico Analysis.

Debasmita MukhopadhyayNour AlSawaftahGhaleb A Husseini

Published in: ACS pharmacology & translational science (2021)

In this study, we investigated the interactions between SARS-CoV-2 and miRNAs associated with lung cancer using bioinformatic approaches. A special focus was placed on TMPRSS2 and lung cancer progression pathways involving AKT/PI3K/PTEN genes.

Keyphrases

pi k akt
sars cov
signaling pathway
cell proliferation
cell cycle arrest
respiratory syndrome coronavirus
bioinformatics analysis
molecular docking
high resolution
cell death
coronavirus disease
genome wide identification
data analysis