[Formula: see text]: ComplexOme-Structural Network Interpreter used to study spatial enrichment in metazoan ribosomes.

Federico Martinez-SeidelYin-Chen HsiehDirk WaltherJoachim KopkaAlexandre Augusto Pereira Firmino

Published in: BMC bioinformatics (2021)

[Formula: see text] offers a computational method to partition multi-protein complexes into structural regions and a statistical approach to test for spatial enrichments of any given subsets of proteins. [Formula: see text] is applicable to any multi-protein complex given appropriate structural and abundance-change data. [Formula: see text] is publicly available as a GitHub repository https://github.com/MSeidelFed/COSNet_i and can be installed using the python installer pip.

Keyphrases

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