Elimination of 15N-thymidine after oral administration in human infants.

Niyatie AmmanamanchiJessie YesterAnita P BargajeDawn ThomasKathryn C LittleShannon JanzefKimberly FrancisJacqueline WeinbergJennifer JohnsonThomas SeeryTyler Hutchinson HarrisBryan J FunariKirsten Rose-FelkerMatthew ZinnSusan A MillerShawn C WestBrian FeingoldHairu ZhouMatthew L SteinhauserTimothy CsernicaRobert MichenerBernhard Kühn

Published in: PloS one (2024)

The presented results support two conclusions of significance for future applications: (1) Demonstration that 15N-thymidine label administration at home is equivalent to in-hospital administration. (2) Two different types of heart disease show no differences in 15N-thymidine absorption and elimination. This enables the comparative analysis of cellular proliferation between different types of heart disease.

Keyphrases

pulmonary hypertension
endothelial cells
healthcare
signaling pathway
induced pluripotent stem cells
current status
emergency department
adverse drug