Patient preferences and adherence to adjuvant GnRH analogs among premenopausal women with hormone receptor positive breast cancer.
Jasmine S SukumarDionisia QuirogaMahmoud KassemMichael GrimmNamrata Vilas ShindeLeslie AppiahMarilly PalettasJulie StephensMargaret E Gatti-MaysAshley PariserMathew CherianDaniel G StoverNicole WilliamsJeffrey Van DeusenRobert WesolowskiMaryam LustbergBhuvaneswari RamaswamySagar D SardesaiPublished in: Breast cancer research and treatment (2021)
Non-adherence to adjuvant GnRHa occurred in over a third of patients and almost half the patients initiating GnRHa underwent subsequent surgical ablation. These high frequencies highlight real-world patterns of OFS. Additionally, treatment toxicities may impact personal preference of OFS modality. Personalized practices to target predictors of adjuvant GnRHa non-adherence are critical to optimize symptoms, adherence, and survivorship.
Keyphrases
- end stage renal disease
- early stage
- ejection fraction
- newly diagnosed
- chronic kidney disease
- positive breast cancer
- healthcare
- prognostic factors
- primary care
- type diabetes
- physical activity
- metabolic syndrome
- patient reported outcomes
- adipose tissue
- replacement therapy
- combination therapy
- breast cancer risk
- structure activity relationship