Combined study of ADAMTS13 and complement genes in the diagnosis of thrombotic microangiopathies using next-generation sequencing.
Teresa FidalgoPatrícia MartinhoCatarina S PintoAna C OliveiraRamon SalvadoNina BorràsMargarida CouceloLicínio MancoTabita MaiaM João MendesRafael Del Orbe BarretoIrene CorralesFrancisco VidalM Letícia RibeiroPublished in: Research and practice in thrombosis and haemostasis (2017)
Our study provides evidence of the usefulness of the NGS panel as an excellent technology that enables more rapid diagnosis of TMA, and is a valuable asset in clinical practice to discriminate between TTP and aHUS.