Early Mortality of Brain Cancer Patients and its Connection to Cytomegalovirus Reactivation During Radiochemotherapy.
Nicole L GoerigBenjamin FreyKlaus KornBernhard FleckensteinKlaus ÜberlaManuel Alexander SchmidtArnd DörflerTobias EngelhornIlker EyüpogluPaul F RühleFlorian PutzSabine SemrauUdo S GaiplRainer FietkauPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2020)
For patients with brain cancer, HCMV reactivation after the start of radiochemotherapy is a frequent risk for cognitively detrimental but treatable encephalopathy and premature death. Routinely performed HCMV diagnostics, assessing basophil counts and study-based anti-viral regimens, are necessary to combat this hidden threat.See related commentary by Lawler et al., p. 3077.
Keyphrases
- resting state
- white matter
- locally advanced
- papillary thyroid
- cerebral ischemia
- functional connectivity
- cardiovascular events
- cognitive decline
- epstein barr virus
- early onset
- mild cognitive impairment
- multiple sclerosis
- risk factors
- type diabetes
- squamous cell carcinoma
- peripheral blood
- brain injury
- lymph node metastasis
- blood brain barrier
- subarachnoid hemorrhage