The impact of histologic subtype on primary site surgery in the management of metastatic lobular versus ductal breast cancer: a population based study from the National Cancer Database (NCDB).
Harriet T RothschildElle N ClellandMary Kathryn AbelAmy Jo ChienAmy M ShuiLaura J EssermanSeema Ahsan KhanRita A MukhtarPublished in: Breast cancer research and treatment (2023)
Lobular histology is associated with less primary site surgery, higher positive margin rates, less radiotherapy and chemotherapy, and shorter OS compared to those with HR-positive HER2-negative IDC. These findings support the need for ILC-specific data and treatment approaches in the setting of metastatic disease.
Keyphrases
- minimally invasive
- coronary artery bypass
- squamous cell carcinoma
- small cell lung cancer
- locally advanced
- surgical site infection
- early stage
- radiation therapy
- big data
- young adults
- machine learning
- coronary artery disease
- combination therapy
- percutaneous coronary intervention
- rectal cancer
- artificial intelligence