The Effect of Antibiotic Restriction Programs on Prevalence of Antimicrobial Resistance: A Systematic Review and Meta-Analysis.

Emelie C SchutsAnders BoydAnouk E MullerJohan W MoutonJan M Prins

Published in: Open forum infectious diseases (2021)

We could not confirm that restricting carbapenems or third-generation cephalosporins leads to decrease in prevalence of antibiotic resistance among Enterobacterales, nonfermenters, or Gram-positive bacteria in hospitalized patients. Nevertheless, reducing fluoroquinolone and piperacilline-tazobactam use may decrease resistance in nonfermenters.

Keyphrases

antimicrobial resistance
risk factors
gram negative
multidrug resistant