Clinical profile and predictors of viral suppression in HIV-infected older adults at a University Hospital in Kumasi, Ghana.
Nana Kwame Ayisi-BoatengDouglas Aninng Opoku AnningIsaac NkrumahBernard FrempongMichael OwusuEric OduroBrenda Abena AmpahEmmanuel KonaduBetty NormanPublished in: AIDS care (2022)
Availability of effective antiretroviral therapy (ART) has improved patient survival and older adults (≥50 years old) constitute 10% of the world's HIV population. However, data on this population are lacking, especially in sub-Saharan Africa. To identify the profile of older adults with HIV infection receiving ART and factors associated with viral suppression. A retrospective cross-sectional study involving HIV patients ≥50 years, registered at a University Hospital in Kumasi, Ghana from January 2010 to July 2020. All study participants had been on ARTs for ≥12 months. Data were analysed using STATA ® and multivariate logistic regression was done to determine the association between variables. We recruited 132 study participants with a mean age of 58.1 years (±6.8). Non-communicable diseases (NCD) comprised the commonest comorbidity (67.4%; n = 89) and hypertension was the most prevalent (47.2%). The mean duration of ART was 63.2 months (±32.0) and approximately 84.1% ( n = 111) achieved viral suppression (≤50 copies/ml). After adjustment, factors independently associated with viral suppression were widow(ed) (aOR = 0.23; 95% CI = 0.07-0.72) and good ART adherence (aOR = 3.51; 95% CI = 1.03-11.99). Hypertension is prevalent among this cohort of HIV patients. Approximately 84% of elderly patients on ARTs achieve viral suppression, influenced by widowhood and good drug adherence.
Keyphrases
- antiretroviral therapy
- hiv infected
- human immunodeficiency virus
- hiv positive
- hiv infected patients
- hiv aids
- sars cov
- end stage renal disease
- ejection fraction
- blood pressure
- newly diagnosed
- physical activity
- chronic kidney disease
- emergency department
- type diabetes
- hepatitis c virus
- case report
- adipose tissue
- hiv testing
- patient reported outcomes
- south africa
- metabolic syndrome
- middle aged
- men who have sex with men
- drug induced