A combination of genomics and transcriptomics provides insights into the distribution and differential mRNA expression of type VI secretion system in clinical Klebsiella pneumoniae .

Wanzhen LiXiaolan HuangDan LiXiao-Fen LiuXiaoying JiangXingchen BianXin Li

Published in: mSphere (2024)

. This study also described the overall transcriptional changes in the predominant Chinese ST11 strain HS11286 upon deletion of crucial T6SS genes. Additionally, this work provides a reference for future research on the identification of T6SS in bacteria.

Keyphrases

klebsiella pneumoniae
single cell
multidrug resistant
escherichia coli
bioinformatics analysis
gene expression
genome wide
transcription factor
oxidative stress