Leu72Met polymorphism of GHRL gene decreases susceptibility to type 2 diabetes mellitus in a Mexican population.

Edgar Alfonso Rivera-LeónMara Anaís Llamas-CovarrubiasSergio Sánchez-EnríquezErika Martínez-LópezMercedes González-HitaIris Monserrat Llamas-Covarrubias

Published in: BMC endocrine disorders (2020)

The GHRL 72Met allele decreases susceptibility for T2D development in a Western Mexican population. Serum ghrelin levels are lower in T2D independently of Leu72Met polymorphism genotype.

Keyphrases

tyrosine kinase
copy number
south africa
genome wide
gene expression
type diabetes
cardiovascular disease
metabolic syndrome
dna methylation
transcription factor
genome wide identification
insulin resistance