Notch Signaling Pathway Is Inhibited in the Development of Barrett's Esophagus: An In Vivo and In Vitro Study.

Yun-Cang WangZhi-Qiang WangYong YuanTao RenPeng-Zhi NiLong-Qi Chen

Published in: Canadian journal of gastroenterology & hepatology (2018)

Both hydrochloric acid and deoxycholic acid could suppress Notch signaling pathway in esophageal epithelial cells, and inhibited Notch signaling has important functions in the development of Barrett's esophagus.

Keyphrases

signaling pathway
pi k akt
cell proliferation
epithelial mesenchymal transition
induced apoptosis