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Are local analgesics effective in reducing autonomic dysreflexia in individuals with spinal cord injury? A systematic review.

Katherine GrayWhitley SheehanLaura McCrackenKlaus KroghRahul SachdevaAndrei V Krassioukov
Published in: Spinal cord (2022)
Presently, RCTs and quasi-experimental studies on the use of lidocaine for reducing AD in individuals with SCI had small sample sizes and opposing findings. There is a strong need for definitive, well-monitored clinical trials with adequate sample sizes. Presently there is not enough compelling evidence to support or refute recommendations for the use of lidocaine from the AD management clinical practice guidelines.
Keyphrases
  • clinical trial
  • spinal cord injury
  • heart rate variability
  • heart rate
  • clinical practice
  • locally advanced
  • squamous cell carcinoma
  • blood pressure
  • phase ii
  • case control
  • radiation therapy