Peripheral Blood Single-Cell Sequencing Uncovers Common and Specific Immune Aberrations in Fibrotic Lung Diseases.

Amy Y ZhaoAvraham UntermanNebal Abu HusseinPrapti SharmaJasper FlintXiting YanTaylor S AdamsAurelien JustetTomokazu S SumidaJiayi ZhaoJonas C SchuppMicha Sam B RaredonJonas Christian SchuppYingze ZhangIvette Buendia-RoldanAyodeji AdegunsoyeAnne I SperlingAntje PrasseChangwan RyuErica HerzogMoises SelmanAnnie PardoNaftali Kaminski

Published in: bioRxiv : the preprint server for biology (2023)

T lymphocytes and T and B cell receptor repertoires were unique in FHP. Our findings open novel strategies for the diagnosis and treatment of IPF and FHP.

Keyphrases

single cell
peripheral blood
idiopathic pulmonary fibrosis
rna seq
minimally invasive
high throughput
copy number
systemic sclerosis
gene expression
binding protein
dna methylation
genome wide