The impact of HIV infection on tuberculosis transmission in a country with low tuberculosis incidence: a national retrospective study using molecular epidemiology.
Joanne R WinterColette J SmithJennifer A DavidsonMaeve K LalorValerie DelpechIbrahim AbubakarHelen R StaggPublished in: BMC medicine (2020)
Outcome 1: pulmonary tuberculosis-HIV patients were less infectious than those without HIV. EPTB patients with HIV who were the first case in a cluster had a higher number of subsequent cases and thus may be markers of other undetected cases, discoverable by contact investigations. Outcome 2: tuberculosis in HIV-positive individuals was more likely due to reactivation than recent infection, compared to those who were HIV-negative.
Keyphrases
- hiv positive
- antiretroviral therapy
- pulmonary tuberculosis
- hiv aids
- men who have sex with men
- hiv infected
- human immunodeficiency virus
- hiv testing
- south africa
- mycobacterium tuberculosis
- hepatitis c virus
- end stage renal disease
- newly diagnosed
- chronic kidney disease
- emergency department
- prognostic factors
- ejection fraction
- risk factors