Outpatient Talc Administration by Indwelling Pleural Catheter for Malignant Effusion.
Rahul BhatnagarEmma K KeenanAnna J MorleyBrennan C KahanAndrew E StantonMohammed HarisRichard N HarrisonRehan A MustafaLesley J BishopLiju AhmedAlex WestJayne HolmeMatthew EvisonMohammed MunavvarPasupathy SivasothyJurgen HerreDavid CooperMark RobertsAnur GuhanClare HooperJames WaltersTarek S SabaBiswajit ChakrabartiSamal GunatilakeIoannis PsallidasSteven P WalkerAnna C BibbySarah SmithLouise J StadonNatalie J Zahan-EvansY C Gary LeeJohn E HarveyNajib M RahmanRobert F MillerNick A MaskellPublished in: The New England journal of medicine (2018)
Among patients without substantial lung entrapment, the outpatient administration of talc through an indwelling pleural catheter for the treatment of malignant pleural effusion resulted in a significantly higher chance of pleurodesis at 35 days than an indwelling catheter alone, with no deleterious effects. (Funded by Becton Dickinson; EudraCT number, 2012-000599-40 .).