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Clustering for epidemics on networks: A geometric approach.

Bastian PrasseKarel DevriendtPiet Van Mieghem
Published in: Chaos (Woodbury, N.Y.) (2021)
Infectious diseases typically spread over a contact network with millions of individuals, whose sheer size is a tremendous challenge to analyzing and controlling an epidemic outbreak. For some contact networks, it is possible to group individuals into clusters. A high-level description of the epidemic between a few clusters is considerably simpler than on an individual level. However, to cluster individuals, most studies rely on equitable partitions, a rather restrictive structural property of the contact network. In this work, we focus on Susceptible-Infected-Susceptible (SIS) epidemics, and our contribution is threefold. First, we propose a geometric approach to specify all networks for which an epidemic outbreak simplifies to the interaction of only a few clusters. Second, for the complete graph and any initial viral state vectors, we derive the closed-form solution of the nonlinear differential equations of the N-intertwined mean-field approximation of the SIS process. Third, by relaxing the notion of equitable partitions, we derive low-complexity approximations and bounds for epidemics on arbitrary contact networks. Our results are an important step toward understanding and controlling epidemics on large networks.
Keyphrases
  • infectious diseases
  • sars cov
  • machine learning
  • single cell
  • convolutional neural network
  • rna seq
  • deep learning
  • case control