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Recent patents on water-soluble polysaccharides for advanced drug delivery, tissue engineering and regenerative medicine.

Samson A AdeyemiYahya Essop Choonara
Published in: Pharmaceutical patent analyst (2022)
Water-soluble polysaccharides have unique properties and have found wide application in the design of advanced drug-delivery systems and the biofabrication of tissue engineered scaffolds in regenerative medicine. This patent review provides a concise incursion into the mechanisms that define the key properties of water-soluble polysaccharides that have found embodiment within active patents recently granted (2020-2021). In addition, the relationship between their solubility and structural features such as molecular weight, ionic profile, degree of branching/crosslinking, side-chain flexibility and the presence/modification of functional groups that have been discusses. An assimilation of patents in which water-soluble polysaccharides are central to the design of therapeutic interventions applied to specialized treatments in oncology, infectious diseases and neuronal disorders is provided.
Keyphrases
  • water soluble
  • tissue engineering
  • infectious diseases
  • drug delivery
  • palliative care
  • physical activity
  • ionic liquid
  • brain injury
  • cerebral ischemia