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Adult phenotype in Koolen-de Vries/KANSL1 haploinsufficiency syndrome.

Simona AmentaSilvia FrangellaGiuseppe MarangiSerena LattanteStefania RicciardiPaolo Niccolò DoronzioDaniela OrteschiChiara VerediceIlaria ContaldoGiuseppe ZampinoMattia GentileEmanuela ScaranoClaudio GrazianoMarcella Zollino
Published in: Journal of medical genetics (2020)
Distinctive features in adult KdVS subjects include intellectual disability, overweight/obesity, behaviour abnormalities with preserved social interest, ability in language, slight worsening of the facial phenotype and no seizures.
Keyphrases
  • intellectual disability
  • autism spectrum disorder
  • weight loss
  • weight gain
  • metabolic syndrome
  • insulin resistance
  • type diabetes
  • healthcare
  • mental health
  • case report