The noncoding circular RNA circHomer1 regulates developmental experience-dependent plasticity in mouse visual cortex.

Kyle R JenksYing CaiMarvin Eduarte NayanKatya TsimringKeji LiJosé C ZepedaGregg R HellerChloe DelepineJennifer ShihShiyang YuanYao ZhuYe WangYangyang DuanAmy K Y FuTaeyun KuDae Hee YunKwanghun ChungChi ZhangEdward S BoydenNikolaos MelliosMriganka SurJacque Pak Kan Ip

Published in: bioRxiv : the preprint server for biology (2024)

mediates synaptic plasticity via Arc-mediated endocytosis of AMPA receptors. Our findings demonstrate circRNA regulation during experience-dependent plasticity and reveal their functional significance and mechanism.

Keyphrases

genome wide
single cell
gene expression
dna methylation