Glycaemic control and hypoglycaemia burden in patients with type 2 diabetes initiating basal insulin in Europe and the USA.
Esmeralda CastelblancoLuigi MeneghiniJochen SeufertLaura LiaoHongwei WangLiyue TongAnna CaliPeter StellaPaulo CaritaKamlesh KhuntiPublished in: Diabetes, obesity & metabolism (2017)
Initiating BI with or without OADs is associated with short- and long-term suboptimal glycaemic control; the majority of patients fail to achieve HbA1c target ≤7% in the first 3 months, or after 2 years of BI treatment. Treatment response and hypoglycaemia incidence by 3 months post BI initiation are associated with longer-term glycaemic control and hypoglycaemic risk, respectively. These results support the need for early anti-hyperglycaemic interventions that more effectively control blood glucose levels without increasing the risk of hypoglycaemia.