Detection of Chemotherapy-resistant Pancreatic Cancer Using a Glycan Biomarker, sTRA.
ChongFeng GaoLuke WisniewskiYing LiuBen StaalIan BeddowsDennis PlenkerMohammed AldakkakJohnathan HallDaniel BarnettMirna Kheir GoudaPeter AllenRichard DrakeAmer ZureikatYing HuangDouglas B EvansAatur SinghiRandall E BrandDavid A TuvesonSusan TsaiBrian B HaabPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2020)
This research demonstrates that a glycan biomarker could have value to detect chemotherapy-resistant PDAC in clinical settings. This capability could aid in the development of stratified treatment plans and facilitate biomarker-guided trials targeting resistant PDAC.