Prognostic value of intra-tumoral CD8+ /FoxP3+ lymphocyte ratio in patients with resected colorectal cancer liver metastasis.
Kostandinos SiderasBoris GaljartAngela VasaturoAlexander Pedroza-GonzalezKatharina BiermannShanta ManchamAlex L NiggBettina E HansenHans A StoopGuoying ZhouCornelis VerhoefStefan SleijferDave SprengersJaap KwekkeboomMarco J BrunoPublished in: Journal of surgical oncology (2018)
The ratio of cytotoxic (CD8+ ) to regulatory (FoxP3+ ) T-cells, in the intra-tumoral compartment, but not in the peri-tumoral compartment, can predict survival after resection of CRCLM.