Development of a physiologically based pharmacokinetic (PBPK) population model for Chinese elderly subjects.

Dongyang LiuJie En Valerie SiaSiqi TuXiaobei LiZhongqi DongZhiheng YuXueting YaoOliver HatleyHaiyan LiDongyang Liu

Published in: British journal of clinical pharmacology (2021)

The population model for the Chinese elderly subjects appears to adequately predict the concentration of the drug that was metabolized by CYP1A2, CYP3A4 or eliminated by renal clearance.

Keyphrases

middle aged
community dwelling
emergency department
electronic health record